To understand the system and predict the key parameters which influence the dissolution of respirable size particles, a simulation model was constructed using STELLA modeling software.
A dissolution apparatus has been custom-made for dissolution testing of dry powder formulations in a small volume of stationary medium (25 μL spread over 4.91 cm 2 area i.e.
In vitro dissolution testing is a useful quality control tool to discriminate the formulations and to approximate the in vivo drug release profiles.
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